Formulation and Characterization of Patient-Friendly Dosage Form of Ondansetron Hydrochloride
نویسندگان
چکیده
منابع مشابه
Formulation and Characterization of Patient-Friendly Dosage Form of Ondansetron Hydrochloride
Ondansetron hydrochloride is an intensely bitter antiemetic drug used to treat nausea and vomiting following chemotherapy. The purpose of the present work was to mask the taste of ondansetron hydrochloride and to formulate its patient-friendly dosage form. Complexation technique using indion 234 (polycyclic potassium with carboxylic functionality) and an ion-exchange resin was used to mask the ...
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Aim: The objective of the present research work was to develop stable extended release (ER) pellets of propranolol hydrochloride, an antihypertensive drug, for which drug release profi le is compared with reference to the multiple conventional dosage form i.e. marketed product “Inderal LA” (160 mg). Method: ER formulations were developed using fl uid bed layering and coating techniques on sugar...
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sustained release oral delivery systems are designed to achieve therapeutically effective concentrations of drug in the systemic circulation over an extended period of time. the purpose of the present investigation was to design and evaluate sustained release matrix tablets of nifedipine, a poorly water soluble drug, employing hydroxypropyl methyl cellulose ( hpmc) and ethyl cellulose ( ec) as ...
متن کاملFormulation and Evaluation of Transdermal Films of Ondansetron Hydrochloride
Transdermal delivery of ondansetron hydrochloride is one of the promising ways to maximize the therapy in contrast to oral delivery. Current investigation efforts are focused in formulating the ondansetron hydrochloride matrix-type transdermal film by incorporating hydrophilic and hydrophobic polymers. In this study, ondansetron hydrochloride transdermal films were prepared using solvent evapor...
متن کاملFormulation Development and Evaluation of Ondansetron Hydrochloride Nasal Spray
The objective of the present study was to formulate and evaluate nasal delivery system contains Ondansetron hydrochloride 4 mg/ml. Ondansetron hydrochloride loaded colloidal dispersion were prepared for nasal drug delivery using various polymers like β-cyclodextrin, hydroxyl propyl βcyclodextrin at different concentrations. The optimized formulation contains 0.02% benzalkonium chloride as a pre...
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ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2010
ISSN: 0975-1483
DOI: 10.4103/0975-1483.66796